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Monday, October 13 2008      

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         Article Summary  

Parkinson's Drug Pulled from US Market
(AFP, 3/30/07)

The FDA announced that the manufacturers of the Parkinson's drug pergolide, marketed as Permax and in two generic forms, will stop selling it in the US based on evidence that demonstrate that it significantly raises the risk of heart valve damage. Two studies in the New England Journal of Medicine confirm previous findings linking pergolide to a condition known as valve regurgitation, where the valves do not close tightly enough to block the backflow of blood. The FDA advised patients to contact their doctors and not just abruptly discontinue the medication.

 

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