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Thursday, August 28 2008      

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         Article Summary  

Hormone May Combat Mid-Life Depression
(Chicago, Reuters Health, 2/7/05)

The US National Institute of Mental Health reports that a study of 46 depressed adults, aged 45 to 65, demonstrated that dehydroepiandrosterone (DHEA) may effectively control mid-life depression for some people. Participants in the study were given either DHEA, an adrenal hormone, or a placebo; then the DHEA and placebo groups were switched. In 23 subjects, there was a reduction of at least 50% in their depression after they received DHEA; while 13 improved after the placebo. The researchers concluded that DHEA may be a useful alternative for patients not responding to conventional antidepressants or who are unwilling to take them.

(Archives of General Psychiatry)

 

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