Busy Minds May Slow Alzheimers
 (HealthDayNews, 3/10/05)

Sangram Sisodia of the University of Chicago, and team, studied mice that had been genetically engineered to develop clumping of amyloid proteins around their brain cells, similar to what happens in human Alzheimer's patients. The researchers placed some of these animals in a stimulating environment with toys, wheels and tunnels; while they put others in bland surroundings. The under-stimulated mice developed more brain plaque and protein buildup than the active mice because the brains of the stimulated mice were apparently better able to clear amyloid peptides. These findings suggest that an environment that fosters greater physical and mental activity may help protect against the debilitating effects of Alzheimer’s disease.

(Cell Press, news release, March 10, 2005)