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Wednesday, December 03 2008      

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         Article Summary  

Common Drug for Knee Pain No Better Than Placebo
 (NY, Reuters Health, 8/6/04)

Dr. Maxime Dougados, of Rene Descartes University, Paris, and team, randomly assigned either a placebo or 4 grams a day of paracetamol (also called acetaminophen), the active ingredient in Tylenol, to 779 patients who had knee pain due to osteoarthritis. After 6 weeks, slightly over half of the subjects in both groups experienced at least a 30% decrease in pain intensity. Further studies will have to be conducted to find out why participants receiving paracetamol appeared to have no greater symptomatic relief of osteoarthritis knee pain than the placebo group.

(Annals of the Rheumatic Diseases, August 2004

 

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